Differential expression of mucin 1 and mucin 2 in colorectal cancer

Table 3 Tissue expression of mRNA and proteins of both mucins, mucin 1/mucin 2 ratio in colorectal carcinoma and in unaltered colorectal tissue

		Group	Number	Mean	Median	Min	Max	SD	aP value
MUC1	mRNA	CRC	23	75095	49309	5648	267473	72149	0.004
		Control	23	32413	20075	2	199681	44486
	Protein	CRC	34	2.57	1.64	0.33	9.80	2.24	0.627
		Control	32	2.16	1.72	0.00	6.54	1.64
MUC2	mRNA	CRC	23	350227	191457	2806	2399156	529270	0.274
		Control	23	219744	130691	1	1509936	324252
	Protein	CRC	34	4.94	2.15	0.20	32.30	7.24	0.035
		Control	32	7.40	5.15	0.73	31.60	6.77
MUC1/MUC2 ratio	mRNA	CRC	23	1.56	0.25	0.06	21.30	4.50	0.128
		Control	23	0.28	0.18	0.04	2.00	0.40
	Protein	CRC	34	1.84	0.80	0.04	10.35	2.54	0.003
		Control	32	0.52	0.37	0.00	1.95	0.51

Control: Unaltered colorectal tissue;

^aP: Comparing colorectal carcinoma and control. MUC1: Mucin 1; MUC2: Mucin 2; SD: Standard deviation; CRC: Colorectal carcinoma.