Gastroduodenal ulcer bleeding in elderly patients on low dose aspirin therapy

Table 2 Characteristics of the medicated vs non-medicated groups and the elderly vs non-elderly groups

	Medicated group (n = 474)	Non-medicated group (n = 631)	P value	Elderly group (n = 436)	Non-elderly group (n = 669)	P value
Mean age (yr)	69.7	60.4	< 0.001	78.5	54.9	< 0.001
Sex (male:female)	352:122	491:140	< 0.001	271:165	552:117	< 0.001
Hb (mg/L)	82.6	91.1	< 0.001	80.8	91.9	< 0.001
H. pylori infection (positive:negative)	73.5% (324:117)	89.3% (533:64)	< 0.001	77.9% (311:88)	85.4% (546:93)	0.002
Single ulcer	61.4% (291:183)	74.2 (468:163)	< 0.001	40.1% (175:261)	25.6% (171:498)	< 0.001
ForrestI	25.7% (122:352)	21.7% (137:494)	0.118	25.5% (11:325)	22.1% (148:521)	0.201
Anti-ulcer medication	52.1% (247:227)	17.3% (109:522)	< 0.001	41.3% (189:256)	26.3% (176:493)	< 0.001
Underlying disease
Cardiac disease	43.0% (204:270)	7.9% (50:581)	< 0.001	33.9% (148:288)	15.8% (106:563)	< 0.001
Cerebrovascular disorder	25.9% (123:351)	4.0% (25:606)	< 0.001	22.2% (97:339)	7.6% (51:618)	< 0.001
Renal disease	16.5% (78:396)	7.4% (47:584)	< 0.001	13.1% (57:379)	10.2% (68:601)	0.136
Respiratory disease	13.5% (64:410)	8.1% (51:580)	0.003	14.9% (65:371)	7.5% (50:619)	< 0.001
Orthopedic disorder	28.9% (137:337)	4.0% (25:606)	< 0.001	21.6% (94:342)	10.2% (68:601)	< 0.001
History of ulcer	21.9% (104:370)	28.7% (181:450)	< 0.001	18.3% (80:356)	30.6% (205:464)	< 0.001
Hypertension	41.4% (196:278)	25.9% (158:473)	< 0.001	45.2% (197:239)	23.5% (157:512)	< 0.001
DM	21.7% (103:371)	15.1% (95:536)	0.004	18.3% (80:356)	17.6% (118:551)	0.763

Hb: Hemoglobin; H. pylori: Helicobacter pylori; DM: Diabetes mellitus.