Low expression of CDK5RAP3 and DDRGK1 indicates a poor prognosis in patients with gastric cancer

Table 4 Multivariate analysis of the correlation between clinicopathological parameters and survival time of patients with gastric cancer

Covariates	Coefficient	Standard error	HR	95%CI for HR	P value
CDK5RAP3 expression (high vs low)	-1.226	0.735	0.294	0.070-1.239	0.095
DDRGK1 expression (high vs. low)	-0.979	0.536	0.376	0.131-1.074	0.068
CDK5RAP3 and DDRGK1 expression (low/low vs. high and/or high)	1.178	0.453	3.247	1.336-7.891	0.009
Depth of invasion (T3,T4 vs T1,T2)	1.071	1.045	2.920	0.376-22.635	0.305
Lymph node metastasis (positive vs negative)	1.538	1.020	1.974	0.631-34.367	0.132
Distant metastasis (positive vs negative)	0.861	0.544	2.365	0.815-6.8631	0.113
TNM stage (stage III and IV vs I and II)	-1.630	0.608	7.195	0.060-0.645	0.007