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©The Author(s) 2018.
World J Gastroenterol. Sep 7, 2018; 24(33): 3749-3759
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3749
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3749
Figure 6 Expression of p53 and some of its targets in HROC57 cells.
Western Blot analysis of untreated HROC57 cells compared to HCT116 (p53 wildtype) and HCT116 p53-/- was performed. Acetylation (K382) and phosphorylation (S15) of p53 (A) and expression of its targets p21, survivin and HDAC 1 and 2 (B) were assessed using specific antibodies. HSP90 served as loading control. Numbers indicate densitometric analysis of respective signals normalized to loading control and relative to HCT116 cells.
- Citation: Gock M, Mullins CS, Harnack C, Prall F, Ramer R, Göder A, Krämer OH, Klar E, Linnebacher M. Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line. World J Gastroenterol 2018; 24(33): 3749-3759
- URL: https://www.wjgnet.com/1007-9327/full/v24/i33/3749.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i33.3749