Metabolomic alterations and chromosomal instability status in gastric cancer

doi:10.3748/wjg.v24.i33.3760

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 24, Issue 33

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (8283)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-5) series.

Item

Count

PDF

737

WORD

313

HTML

4176

Figures (1-3)

356

Tables (1-5)

287

Sum=5869

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1151

Download

1263

Sum=2414

Sep 7, 2018 (publication date) through Feb 12, 2025

Times Cited of This Article

Times Cited (21)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. Sep 7, 2018; 24(33): 3760-3769
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3760

Table 5 Altered metabolites with statistical significance between chromosomal instability and non-chromosomal instability types

	Metabolites		VIP score (VIP > 1.2)	Fold change (tumor/healthy > 1.2 or < 0.8)	P value (P < 0.05)
CIN tumor	Increased	Aspartic acid	1.309	2.029	0.043
		Citicoline	1.751	2.886	0.033
		Glutamic acid	1.219	2.101	0.011
		Oxidized glutathione	1.642	2.249	0.018
		Succinyladenosine	1.671	3.434	0.011
		Uridine diphosphate-N-acetylglucosamine	1.264	2.006	0.036
	Decreased	Butyrylcarnitine	1.218	0.590	0.014
		Glutathione	1.214	0.582	0.042
		Hydroxyhexanoycarnitine	1.883	0.397	0.013
		Inosinic acid	1.572	0.506	0.008
		Isovalerylcarnitine	1.657	0.346	0.004
		Threonine	1.714	0.394	0.006
non-CIN tumor	Increased	Glutamic acid	1.424	1.688	0.031
		Oxidized glutathione	1.678	1.676	0.019
		Proline	1.542	1.569	0.003
		Succinyladenosine	1.929	3.207	0.031
		Xanthine	2.360	2.085	0.007
	Decreased	NAD	1.584	0.599	0.047

VIP: Variable importance in the projection; CIN: Chromosomal instability; NAD: Nicotinamide adenine dinucleotide.

Citation: Tsai CK, Yeh TS, Wu RC, Lai YC, Chiang MH, Lu KY, Hung CY, Ho HY, Cheng ML, Lin G. Metabolomic alterations and chromosomal instability status in gastric cancer. World J Gastroenterol 2018; 24(33): 3760-3769
URL: https://www.wjgnet.com/1007-9327/full/v24/i33/3760.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i33.3760