Metabolomic alterations and chromosomal instability status in gastric cancer

doi:10.3748/wjg.v24.i33.3760

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 7, 2018; 24(33): 3760-3769
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3760

Table 2 Altered metabolites with statistical significance between gastric cancer tumor tissue and its adjacent healthy tissue

Metabolites		VIP score (VIP > 1.2)	Fold change (tumor/healthy > 1.2 or < 0.8)	P value (P < 0.05)
Increased	Butyrylcarnitine	1.204	1.498	0.002
	Hydroxyhexanoycarnitine	2.021	2.342	0.002
	Inosinic acid	1.218	1.720	0.042
	Isovalerylcarnitine	1.424	2.265	0.006
	Threonine	1.316	1.911	0.019
Decreased	Aspartic acid	1.534	0.544	0.004
	Citicoline	1.973	0.371	0.005
	Glutamic acid	1.356	0.536	0.001
	Glutamine	1.221	0.518	0.005
	Isoleucine	1.323	0.593	0.015
	Oxidized glutathione	1.591	0.54	0.008
	Proline	1.231	0.574	0.001
	Succinyladenosine	1.855	0.293	0.001
	Xanthine	1.966	0.443	0.002

VIP: Variable importance in the projection.

Citation: Tsai CK, Yeh TS, Wu RC, Lai YC, Chiang MH, Lu KY, Hung CY, Ho HY, Cheng ML, Lin G. Metabolomic alterations and chromosomal instability status in gastric cancer. World J Gastroenterol 2018; 24(33): 3760-3769
URL: https://www.wjgnet.com/1007-9327/full/v24/i33/3760.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i33.3760