Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line

doi:10.3748/wjg.v24.i33.3749

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Sep 7, 2018 (publication date) through Dec 31, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 7, 2018; 24(33): 3749-3759
Published online Sep 7, 2018. doi: 10.3748/wjg.v24.i33.3749

Table 2 Measured IC₅₀ values and selected human plasma reference levels of analyzed chemotherapeutic agents

Drug	IC₅₀	Plasma reference
5-FU	10.53 μg/mL	50 μg/mL[44]
SAHA	0.249 μg/mL
Oxaliplatin	701 ηg/mL	2 μg/mL[45]
Folfox	5.48 μg/mL + 137.1 ηg/mL
Irinotecan	0.745 μg/mL	1 μg/mL[46]
Folfiri	1 μg/mL + 0.674 μg/mL
Rapamycin	4.8 μg/mL	5-100 mg/L[47]

References for human plasma levels are set in brackets. SAHA: Suberoylanilide hydroxamic acid.

Citation: Gock M, Mullins CS, Harnack C, Prall F, Ramer R, Göder A, Krämer OH, Klar E, Linnebacher M. Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line. World J Gastroenterol 2018; 24(33): 3749-3759
URL: https://www.wjgnet.com/1007-9327/full/v24/i33/3749.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i33.3749