Abnormal expression of HMGB-3 is significantly associated with malignant transformation of hepatocytes

Figure 5 Silencing HMGB3 suppressed growth of xenograft tumor. HepG2 cells transfected with NC-shRNA and shRNA-1 were subcutaneously injected into mice. A: The morphology of the xenograft tumor in the NC-shRNA or shRNA-1 group at 30^th d. B: The growth curves of tumors derived from HepG2 cells in the NC-shRNA or shRNA-1 group. C: The weight of xenograft tumors in the NC-shRNA or shRNA-1 group. D: The immunochemical staining of HMGB3 and Ki67 in xenograft tumor tissues in the NC-shRNA or shRNA-1 group. ^bP < 0.01.