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©The Author(s) 2018.
World J Gastroenterol. Aug 28, 2018; 24(32): 3626-3636
Published online Aug 28, 2018. doi: 10.3748/wjg.v24.i32.3626
Published online Aug 28, 2018. doi: 10.3748/wjg.v24.i32.3626
Table 2 Results after liver transplantation with expanded criteria
Ref. | Type | Patients,n (type) | Criteria (findings) | Survival,time (%) | Recurrence,time (%) | Factorsfor survival | Factorsfor recurrence |
Yao et al[9], 2001 | R | 14 (MO) | UCSF (Histol) | 5 yr (84.6) | - | pT4, total tumor diameter | - |
Yao et al[27], 2007 | P | 38 (MO) | UCSF (Radiol) | 5 yr DFS (93.6) | UCSF Vascular invasion AFP > 1000 ng/mL | ||
Onaca et al[32], 2007 | R | 129 (MO) | Onaca | 5 yr DFS (63.9) | Tumor > 6 cm AFP > 200 ng/mL Tumors > 4 | ||
Herrero et al[28], 2008 | P | 26 (MO) | CUN (Radiol) | 5 yr (73) 5 yr I-to-T (68) | Vascular invasion | ||
Zheng et al[13], 2008 | R | 99 (MI and MO), 26 (MO) | Hangzhou (Histol) | 5 yr (70.7) | 5 yr DFS (62.4) | Macrovascular invasion Tumor size > 8 cm AFP > 400 ng/mL Histological grading (III) | Macrovascular invasion Tumor size > 8 cm AFP > 400 ng/mL Histological grading (III) |
Mazzaferro et al[10], 2009 | R | 283 (MI and MO) | Up-to-seven (Histol) | 5 yr (71.2) | - | Microvascular invasion Tumor grade | - |
Toso et al[29], 2015 | P | 38 (MO) | Toso (Radiol) | 4 yr (74.6) 4 yr I-to-T (53.8) | 4 yr DFS (68) | - | - |
Togashi et al[54], 2016 | R | 14 (MO) | Tokyo | - | 5 yr (8) | - | Tokyo criteria AFP ≥ 400 ng/mL DCP ≥ 200 mAU/mL |
Kaido et al[56], 2013 | R | 42 (MO) | Kyoto | 5 yr (80) | 5 yr (7) | Kyoto criteria Pretreatment of the HCC | |
Shirabe et al[57], 2011 | R | 48 (MI and MO) | Kyushu (Histol) | 5 yr DFS (80) | Kyushu criteria | ||
Lee et al[58], 2008 | R | 174 (MI and MO) | Asan (Histol) | 5 yr (81.6) | 5 yr (15) | Largest tumor > 5 cm Number > 6 Gross vascular invasion | Largest tumor > 5 cm Number > 6 Gross vascular invasion |
Kim et al[59], 2014 | R | 180 (in the whole study, including Samsung-out) | Samsung (Histol) | 5 yr DFS -89.6 | Tumors ≤ 7 Diameter ≤ 6 cm AFP ≤ 1000 ng/mL | ||
Llovet et al[14], 2018 | P | 22 | BCLC (Radiol) | 5 yr (80.2) | 5 yr (23.8) | MI after locoregional therapies |
- Citation: Pavel MC, Fuster J. Expansion of the hepatocellular carcinoma Milan criteria in liver transplantation: Future directions. World J Gastroenterol 2018; 24(32): 3626-3636
- URL: https://www.wjgnet.com/1007-9327/full/v24/i32/3626.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i32.3626