Altered oral microbiota in chronic hepatitis B patients with different tongue coatings

doi:10.3748/wjg.v24.i30.3448

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 24, Issue 30

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (9478)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-5) series, Tables (1-2) series.

Item

Count

PDF

489

HTML

4680

Figures (1-5)

398

Tables (1-2)

563

Sum=6130

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1075

Download

2273

Sum=3348

Aug 14, 2018 (publication date) through Dec 28, 2024

Times Cited of This Article

Times Cited (29)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Observational Study

World J Gastroenterol. Aug 14, 2018; 24(30): 3448-3461
Published online Aug 14, 2018. doi: 10.3748/wjg.v24.i30.3448

Table 1 Physiological characteristics of the subjects

	Healthy	CHB patients		P value
	Healthy	White tongue coating	Yellow tongue coating	P value
Age	34.09 ± 7.16	34.46 ± 9.92	38.08 ± 9.89	0.255
Gender, male/female	13/9	21/7	17/8	0.488
BMI (kg/m²)	21.22 (16.61-25.56)	23.44 (18.42-31.64)	23.30 (18.37-45.67)	0.077
Antiviral drugs (%)	/	78.60%	64%	0.24
Chinese herbs (%)	/	17.90%	28%	0.378
TBIL (μmol/L)	14.87 (8.29-31.62)	12.85 (7.9-27.7)	17.27 (6.4-45.6)	0.27
DBIL (μmol/L)	3.065 (1.7-6.76)	3.9 (1.64-9.2)	4.8 (2.05-34.7)^b	0.006
IDBIL (μmol/L)	11.6 (6.3-25.7)	8.95 (5-18.7)	10.2 (4.2-19.6)	0.282
ALT (IU/L)	15 (10-34)	28.75 (8.5-170)^b	47 (11.1-533)^c	< 0.001
AST (IU/L)	17.5 (11-31)	27 (12-133)^b	38 (14.8-543)^c	< 0.001
ALP(IU/L)	15.28 (9-52)	25.8 (10.01-98)	38 (8.6-274)^c	< 0.001
GGT (IU/L)	70.5 (35-119)	72.7 (37.1-131)	76.3 (41.7-202)	0.62
ALB (g/L)	44.97 (40.89-50.77)	48.7 (43.1-56.3)^a^d	46 (36.6-50.1)	0.003
PT (s)	12.55 (11.3-13.9)	12.7 (11.1-16.4)	13.3 (11.3-16)	0.032
HBV-DNA (IU/mL)	/	500 (500-44830000)^d	21210 (500-324100000)	0.03
BUN (mmol/L)	4.39 (2.97-6.39)	4.96 (2.96-8.9)	4.2 (2.4-7.28)	0.074
Gr (μmol/L)	72.355 (45.1-106.67)	70 (27.4-96.7)	69 (35.9-83)	0.449
UN (μmol/L)	305.5 (201-406)	325 (207-550)	294 (154-429)	0.204
FPG (mmol/L)	5.2 (3.96-5.63)	5.2 (4.29-7.09)	5.215 (4.07-15.54)	0.532
TC (mmol/L)	4.04 (0.37-6.34)	4.55 (3.15-6.52)	4.36 (3.1-6.74)	0.102
TG (mmol/L)	0.84 (0.37-1.91)	1.17 (0.58-3.31)^a	1.11 (0.68-2.62)^a	0.008
HDL (mmol/L)	1.14 (0.74-1.76)	1.145 (0.72-1.86)	1.07 (0.58-2.02)	0.779
LDL (mmol/L)	2.205 (1.38-5.04)	2.27 (1.47-3.8)	2.44 (1.12-3.73)	0.647
APOA-A (g/L)	1.175 (0.85-1.62)	1.08 (0.76-1.91)^c	1.02 (0.71-1.42)^c	0.013

Quantitative results are expressed as median with minimum and maximum into brackets. The P values indicate the significance of difference among groups, and the Kruskal-Wallis test for 3 groups and Nemenyi test were used for post pairwise comparisons. The HBV-DNA titers between the chronic hepatitis B (CHB) yellow and white tongue coating patients were compared using the standard non-parametric Mann-Whitney U test. The antiviral drugs usage and the Chinese herbs usage were compared between CHB yellow and white tongue coating patients using the Chi-square test.

^aP < 0.05 vs healthy controls,

^bP < 0.01 vs healthy controls,

^cP < 0.001 vs healthy controls,

^dP < 0.05 vs CHB yellow tongue coating patients.

Citation: Zhao Y, Mao YF, Tang YS, Ni MZ, Liu QH, Wang Y, Feng Q, Peng JH, Hu YY. Altered oral microbiota in chronic hepatitis B patients with different tongue coatings. World J Gastroenterol 2018; 24(30): 3448-3461
URL: https://www.wjgnet.com/1007-9327/full/v24/i30/3448.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i30.3448