Hypoxia preconditioning protects Ca2+-ATPase activation of intestinal mucosal cells against R/I injury in a rat liver transplantation model

Figure 3 Hypoxia preconditioning promotes BCL2 expression in rat intestinal tissues. A: Immunohistochemistry revealed the expression of BCL2 in rat intestinal tissue in the AT and HP groups at postoperative 12 h; B: The ratio of BCL2 expression in the HP group was significantly higher than that in the AT group at postoperative 12 h (HP vs AT P = 0.001); C: The ratio of positive BCL2 expression was detected at several time points postoperatively (2, 6, 12, 24 and 48 h) in the NC, AT, and HP groups. The expression of BCL2 in the HP group was increased after the operation, peaked at postoperative 2 h, and was maintained at a high level. At postoperative 12 h, BCL2 expression in the HP group was significantly higher than that the NC group and the AT group. No significant difference in BCL2 expression was found in the AT group and NC group.