Autoimmune liver disease-related autoantibodies in patients with biliary atresia

Table 5 Association of autoantibodies and prognosis of Kasai procedure with follow-up of 52 biliary atresia patients n (%)

Parameter	Anti-M2-3E		ANA		ANCA
	Positive, n = 17	Negative, n = 35	Positive, n = 8	Negative, n = 44	Positive, n = 29	Negative, n = 23
TB, μmol/L	105.5 ± 80.3	109.4 ± 106.8	41.6 ± 49.5	127.9 ± 135.0	133.0 ± 120.7	85.3 ± 66.2
ALT, U/L	184.1 ± 119.8	171.7 ± 121.4	127.9 ± 135.0	185.8 ± 115.7	171.46 ± 95.5	179.6 ± 140.3
Occurrence of cholangitis	9 (52.9)	20 (57.1)	5 (62.5)	24 (54.5)	24 (82.8)a	5 (21.7)a

Data are described as mean ± SD.

^aP < 0.05, r = 0.61; ANCA showed a positive correlation to the occurrence of postoperative cholangitis. TB is showed as a parameter of persistence of jaundice (TB > 34 μmol/L); ALT is showed as a parameter of acute liver injury (ALT > 35 U/L). ANCAs: Any positivity of ANCAs or specific ANCAs. ALT: Alanine aminotransferase; ANA: Anti-nuclear antibody; ANCA: Anti-neutrophil cytoplasmic antibody; BA: Biliary atresia; TB: Total bilirubin.