Multi-parameter gene expression profiling of peripheral blood for early detection of hepatocellular carcinoma

Table 2 Diagnostic value of the four genes showing P-values less than 0.05

Gene	AUC	P value	95%CI for AUC		Cutoff	Sen	Spe
			Lower	Upper
HGF	0.620	0.014	0.532	0.708	0.102	0.408	0.926
ANXA1	0.697	< 0.001	0.614	0.780	0.919	0.728	0.593
SPAG9	0.761	< 0.001	0.681	0.842	0.477	0.942	0.481
PFN1	0.700	< 0.001	0.620	0.781	0.383	0.437	0.907

P < 0.05 means significant difference. AUC: Area under curve; Sen: Sensitivity; Spe: Specificity.