High expression of type I inositol 1,4,5-trisphosphate receptor in the kidney of rats with hepatorenal syndrome

Figure 1 Histopathology of the liver (HE staining, × 200). A: Group Normal Saline (NS). Normal hepatocytes were arranged in cords; B: Group D-galactosamine (D-GalN) plus lipopolysaccharide (LPS) (G/L). At 12 h, massive hepatocyte necrosis with severe hemorrhage developed; C: Group D-GaIN (G). At 12 h, spotty hepatocyte necrosis was observed; C: Group LPS (L). At 12 h, hepatocytes began to develop necrosis, with incomplete necrosis visible.