Fourth-generation quinolones in the treatment of Helicobacter pylori infection: A meta-analysis

Table 1 Characteristics of studies included in the meta-analysis

Year-Author	Location	H. pylori infection initial diagnosis/re-checking	Control group-Day	Fourth-generation quinolone group-Day	Eradication rate (ITT)(control group/fourth- generation quinolone group)	Eradication rate (PP)(control group/fourth- generation quinolone group)	Compliance	Side effects
2017-Mansour Ghanaei, F	Iran	14C-UBT or histology	BPAC-10	BPAG-10	89% (81/91)/77% (70/91)	91% (81/90)/77.8% (70/90)
2015-Masoodi, M	Iran	13C-UBT, RUT pathology test	OBAC-10	OBAG-10	61.6% (37/60)/66.6% (40/60)	67.2% (37/55)/72.7% (40/55)	97.1%/98.3%	37/19
2014-Rakici, H	Turkey	pistology, stool antigen test	LanAL-10	LanAM-10	89.4% (92/103)/87.8% (93/106)	92% (92/100)/91.8% (93/102)	96%/95.1%	-
2013-Murakami, K	Japan	culture method, RUT, UBT	LanAL-7	LanAS-7	43.1% (28/65)/70% (49/70)	43.7% (28/84)/72.1% (49/68)	98.4%/94.1%	11/11
2012-Zeng, Z	China	14C-UBT	EAC-7	EAM-7	78.9% (180/228)/79.4% (181/228)	82.9% (180/217)/84.2% (181/215)	-	-
2009-Lu, NH	China	14C-UBT	EAC-7	EAM-7	90.3% (28/31)/85.7% (24/28)	-	-	-
2008-Kilic, ZM	Turkey	gastroscopy, histology, RUT, 13C-UBT	RBCAC-14 EAC-14	RBCAM-14	76.7% (23/30)/66.7% (20/30)	76.7% (23/30)/66.7% (20/30)	100%/100%	11/13
				EAM-14	63.3% (19/30)/53.3% (16/30)	63.3% (19/30)/53.3% (16/30)	100%/100%	17/21
2007-Bago, P	Croatia	RUT, histology, culture test, 13C-UBT	LanMetC-7 LanAC-7	LanMetM-7	70.4% (50/71)/93.5% (58/62)	75.8% (50/66)/96.7% (58/60)	-
				LanAM-7	78.2% (61/78)/86.4% (57/66)	80.2% (61/76)/90.5% 57/63)
2005-Kist, M	Germany	13C-UBT	EAC-7 ETC-7	EAM-7	72.5% (58/80)/87.5% (70/80)	78% (58/74)/89% (70/79)	-	-
				ETM-7	75% (60/80)/90% (72/80)	79% (60/76)/92% (72/78)
2005-Nista, EC	Italy	Histological examination, 13C-UBT	ETC-7 EAC-7	ETM-7	75% (60/80)/90% (72/80)	78.9% (60/76)/92.3% (72/78)	-	29/11
				EAM-7	72.5% (58/80)/87.5% (70/80)	78.4% (58/74)/88.6% (70/79)		26/10

A: Amoxicillin; B: Bismuth; C: Clarithromycin; E: Esomeprazole G: Gemifloxacin; Lan: Lansoprazole; L: Levofloxacin; M: Moxifloxacin; Met: Metronidazole; O: Omeprazole; P: Pantoprazole; S: Sitafloxacin; RBC: Ranitidine bismuth citrate; -: Not reported.