Fatigue is not associated with vitamin D deficiency in inflammatory bowel disease patients

Table 4 Univariate and multivariate analysis of chronic fatigue in ulcerative colitis (n = 178)

	Univariate OR (95%CI)		P value	Multivariate OR (95%CI)		P value
Age, years	0.59	0.07, 1.02	0.59
Gender (ref. male)	2.12	1.10, 4.11	0.025	1.80	0.90, 3.62	0.10
25-OH-D < 50 nmol/L (ref)	1.00
25-OH-D 50-75	0.93	0.45, 1.84	0.80
25-OH-D > 75	1.20	0.45, 3.18	0.72
SCCAI ≥ 5	4.81	2.39, 9.67	< 0.01	4.47	2.20, 9.07	< 0.01
CRP ≥ 5 mg/L	1.20	0.57, 2.52	0.63
Calprotectin ≥ 100 mg/kg	1.57	0.73, 3.39	0.25
Depressive symptoms1	3.92	1.64, 9.36	< 0.01	2.55	0.98, 6.64	0.06
Sleep disturbance	2.71	1.33, 5.53	< 0.01	1.40	0.61, 3.19	0.43

¹HADS-D: Hospital Anxiety and depression score - depression subscore ≥ 8. UC: Ulcerative colitis; SCCAI: Simple Clinical Colitis Activity Index; CRP: C-reactive protein.