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©The Author(s) 2018.
World J Gastroenterol. Jul 21, 2018; 24(27): 2984-2994
Published online Jul 21, 2018. doi: 10.3748/wjg.v24.i27.2984
Published online Jul 21, 2018. doi: 10.3748/wjg.v24.i27.2984
Figure 1 Protective effects of aldehyde dehydrogenase 2 on 4-hydroxy-2-nonenal accumulation in ischemia reperfusion injury.
4-hydroxy-2-nonenal (4-HNE) is a pivotal marker for cell damage associated with oxidative stress; its accumulation is prevented by aldehyde dehydrogenase 2 (ALDH2) activation and the action of its agonists. An overwhelming 4-HNE accumulation may also inhibit ALDH2 action. 4-HNE: 4-hydroxy-2-nonenal.
- Citation: Panisello-Roselló A, Lopez A, Folch-Puy E, Carbonell T, Rolo A, Palmeira C, Adam R, Net M, Roselló-Catafau J. Role of aldehyde dehydrogenase 2 in ischemia reperfusion injury: An update. World J Gastroenterol 2018; 24(27): 2984-2994
- URL: https://www.wjgnet.com/1007-9327/full/v24/i27/2984.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i27.2984