Liver intravoxel incoherent motion diffusion-weighted imaging for the assessment of hepatic steatosis and fibrosis in children

Table 3 Univariate linear regression analysis for intravoxel incoherent motion parameters in all groups

	D (× 10-3 mm2/s)			D* (× 10-3 mm2/s)			f (%)			ADC (× 10-3 mm2/s)
	β	SE	P value	β	SE	P value	β	SE	P value	β	SE	P value
AST (IU/L)	-1.389	0.588	0.020a	-0.145	0. 072	0.047a	-0.238	0.266	0.372	-1.146	0.551	0.040a
ALT (IU/L)	-0.304	0.316	0.339	-0.030	0.039	0.445	0.096	0.141	0.496	-0.446	0.294	0.132
PDFF (%)	1.785	1.949	0.362	0.255	0.237	0.284	4.289	0.775	< 0.001a	-0.263	1.826	0.886
T2* (millisecond)	-8.400	4.042	0.040a	0.818	0.495	0.101	-5.002	1.767	0.005a	-4.978	3.814	0.194
MRE (kPa) (n = 103)	-58.819	22.493	0.010a	-8.582	2.672	0.002a	-27.982	7.408	< 0.001a	-33.675	20.407	0.102

^aP < 0.05; IVIM: Intravoxel incoherent motion; ADC: Apparent diffusion coefficient; β: Coefficient; SE: Standard error of the estimated coefficient; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; PDFF: MR proton density fat fraction; MRE: MR elastography.