Impact of the number of examined lymph nodes on outcomes in patients with lymph node-negative gallbladder carcinoma

Table 1 Demographic and tumor characteristics for patients with lymph node-negative gallbladder carcinoma n (%)

Characteristics	Entire cohortn = 893 (100%)	Stage I1n = 228 (25.5%)	Stage II1n = 444 (49.7%)	Stage IIIA1n = 221 (24.7%)	P2Value
Age, yr
Median (range)	67 (21-96)	67 (21-92)	67 (25-96)	67 (35-93)	0.575
Sex
Male	272 (30.5)	63 (27.6)	139 (31.3)	70 (31.7)
Female	621 (69.5)	165 (72.4)	305 (68.7)	151 (68.3)	0.559
Race
White	675 (75.6)	162 (71.1)	34.1 (76.8)	172 (77.8)
Black	106 (11.9)	33 (14.5)	50 (11.3)	23 (10.4)
Others	112 (12.5)	33 (14.5)	53 (11.9)	26 (11.8)	0.261
Grade1
Well	187 (20.9)	67 (29.4)	102 (23.0)	18 (8.1)
Moderate	414 (46.4)	101 (44.3)	215 (48.4)	98 (44.3)
Poor	210 (23.5)	26 (11.4)	96 (21.6)	88 (39.8)
Undifferentiated	11 (1.2)	1 (0.4)	5 (1.1)	5 (2.3)
Unknown	71 (8.0)	33 (14.5)	26 (5.9)	12 (5.4)	< 0.001
Radiation
Yes	151 (16.9)	8 (3.5)	75 (16.9)	68 (30.8)
No	742 (83.1)	220 (96.5)	369 (83.1)	153 (69.2)	< 0.001
Vital status
Alive	547 (61.3)	151 (66.2)	308 (69.4)	88 (39.8)
Dead	346 (38.7)	77 (33.8)	136 (30.6)	133 (60.2)	< 0.001
Number of LN
Median (range)	2 (1-80)	1 (1-80)	2 (1-40)	2 (1-24)	0.590

¹AJCC/TNM 8^th edition.

²Factors were compared by the independent t test and the χ² test for continuous and categorical variables, respectively. LN: Lymph node.