Bioinformatics analysis of aberrantly methylated-differentially expressed genes and pathways in hepatocellular carcinoma

doi:10.3748/wjg.v24.i24.2605

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 24, Issue 24

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (9473)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-5) series, Tables (1-5) series.

Item

Count

PDF

679

HTML

5360

Figures (1-5)

249

Tables (1-5)

610

Sum=6898

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1205

Download

1370

Sum=2575

Jun 28, 2018 (publication date) through Jul 23, 2024

Times Cited of This Article

Times Cited (49)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. Jun 28, 2018; 24(24): 2605-2616
Published online Jun 28, 2018. doi: 10.3748/wjg.v24.i24.2605

Table 4 Hub genes for hypomethylated, highly expressed genes ranked in cytoHubba

Catelogy	Rank methods in cytoHubba
Catelogy	MCC	MNC	Degree	EPC	Closeness	Radiality
Gene symbol top 10	*CDC45*	*CDC45*	*CDC45*	*CDC45*	*CDKN3*	*CDKN3*
	*DTL*	*AURKB*	*AURKB*	*AURKB*	*CDC45*	PRKDC
	RACGAP1	*DTL*	*CDKN3*	*CDKN3*	*AURKB*	*CDC45*
	*AURKB*	RACGAP1	*DTL*	*DTL*	PTTG1	PTTG1
	CDC20	CDC20	RACGAP1	RACGAP1	*DTL*	*MCM10*
	*CDKN3*	*CDKN3*	CDC20	CDC20	*MCM2*	BRCA1
	RRM2	*MCM2*	*MCM2*	*MCM2*	*MCM10*	PI3
	*MCM2*	PTTG1	PTTG1	PTTG1	RACGAP1	*AURKB*
	*MCM10*	RRM2	RRM2	RRM2	CDC20	*MCM2*
	MKI67	*MCM10*	*MCM10*	*MCM10*	RRM2	*DTL*

Bold gene symbols were the overlap hub genes in top 10 by six ranked methods respectively in cytoHubba. MCC: Maximal cilque centrality; MNC: Maximum neighborhood component; Degree: Node connect degree; EPC: Edge percolated component.

Citation: Sang L, Wang XM, Xu DY, Zhao WJ. Bioinformatics analysis of aberrantly methylated-differentially expressed genes and pathways in hepatocellular carcinoma. World J Gastroenterol 2018; 24(24): 2605-2616
URL: https://www.wjgnet.com/1007-9327/full/v24/i24/2605.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i24.2605