Noninvasive imaging of hepatocellular carcinoma: From diagnosis to prognosis

Table 2 Comparison of guidelines of different countries and regions

Region	Year	Country/society	Stratification	Cut-off size	AFP	CEUS	EOB-MRI
Asia	2014	Japan/JSH-LCSG	Dynamic pattern	/	Not included	Included	First-line
	2014	Korea/KLCSG-NCC	Size-based	1 cm	Included	Not included	Preferentially recommended
	2014	India/INASL	Size-based	1 cm	Not included	Included	According to availability
	2017	China/NHFPCPRC	Size-based	2 cm	Included	Included	Optional
	2017	APASL	Dynamic pattern	/	Not included	Included	First-line
Europe	2012	EASL-EORTC	Size-based	1 cm/ 2 cm			Not included
America	2011	USA/AASLD	Size-based	1 cm			Not included

AFP: Alpha fetoprotein; CEUS: Contrast-enhanced ultrasonography; EOB-MRI: Gadoxetic acid-enhanced MRI; JSH-LCSG: Japan Society of Hepatology - Liver Cancer Study Group of Japan; KLCSG-NCC: Korean Liver Cancer Study Group - National Cancer Center; INASL: The Indian National Associa-tion for Study of the Liver; NHFPCPRC: National Health and Family Planning Commission of the Peo-ple’s Republic of China; APASL: Asia-Pacific Association for the Study of the Liver; EASL-EORTC: Eu-ropean Association for the Study of the Liver - European Organization for Research & Treatment of Can-cer; AASLD: The American Association for the Study of Liver Diseases.