Acute kidney injury in acute-on-chronic liver failure is different from in decompensated cirrhosis

Table 4 Cox proportional-hazards model to assess the 90 d death risk

Variables	90-d mortality
	HR (95%CI)	P value
Age	1.022 (1.005-1.039)	0.010
Ascite	2.120 (1.075-4.178)	0.030
HE	5.342 (3.654-7.808)	< 0.001
DC without AKI	Reference	-
ACLF without AKI	3.449 (1.684-7.064)1	0.001
DC with AKI	4.674 (1.977-10.943)1	< 0.001
ACLF with AKI	7.986 (3.823-16.683)1	< 0.001

¹The death risk of patients with DC without AKI were set as reference, HR were adjusted by age, presence of ascites, HE, SBP and leukocyte count. HR: Hazards ratio; HE: Hepatic encephalopathy; SBP: Spontaneous bacterial peritonitis; DC: Decompensated chirrhosis; ACLF: Acute-on -chronic liver failure; AKI: Acute kidney injury.