Magnetic resonance imaging and Crohn’s disease endoscopic index of severity: Correlations and concordance

Table 4 Subgroups in the active Crohn’s disease patients according to disease activity after treatments

	Remained active (n = 17)		Improved to inactive (n = 44)		P value
	Pre-treatment	Post-treatment	Pre-treatment	Post-treatment
Gender (M/F)	10/7		26/18		0.332
Age	30.4 ± 5.5		26.7 ± 10.1		0.563
Disease duration	1-5		1-5
Disease location					0.916
Sigmoid/left colon	1		1
Transverse colon	3		4
Right colon	4		6
Ileum	14		28
Treatment regimen					0.292
Glucocorticoids	8		15
Infliximab	6		12
Adalimumab	3		17
CRP	28.01 ± 5.22		20.91 ± 5.45		0.054
CDEIS	12.23 ± 5.12	10.47 ± 3.43	10.12 ± 2.11	3.11 ± 0.21	0.001
CRP	28.01 ± 5.215	15.12 ± 4.32	20.91 ± 5.45	5.84 ± 0.743	0.002
ADC	1.52 ± 0.12	1.44 ± 0.34	1.59 ± 0.17	1.73 ± 0.2	0.001
Thickness	9.12 ± 1.21	7.66 ± 1.41	8.2 ± 2.22	5.42 ± 1.32	0.012
tRCE	89.14 ± 13.33	69.49 ± 12.11	82.11 ± 12.47	45.32 ± 4.53	0.021
aRCE	179.03 ± 20.66	166.16 ± 22.44	181.14 ± 34.1	89.76 ± 12.71	0.001
pRCE	330.02 ± 67.12	285.27 ± 57.71	301.32 ± 54.12	199.23 ± 23.2	0.001
dRCE	453.29 ± 54.05	385.5 ± 45.32	440.18 ± 33.09	257.22 ± 44.13	0.001
MaRIA
tREC	35.17 ± 5.66	30.12 ± 3.12	26.56 ± 2.90	6.23 ± 1.11	< 0.001
aRCE	28.22 ± 6.76	19.12 ± 4.09	29.47 ± 5.22	6.48 ± 1.38	< 0.001
pRCE	37.79 ± 5.59	29.21 ± 4.21	36.28 ± 4.72	7.11 ± 1.74	< 0.001
dRCE	36.09 ± 8.12	25.2 ± 5.77	27.08 ± 5.79	7.22 ± 1.59	< 0.001
ESR	24.186 ± 3.210	18.28 ± 3.38	21.49 ± 3.33	3.184 ± 0.568	< 0.001

CRP: C-reactive protein; ADC: Apparent diffusion coefficient; tRCE: Total relative contrast enhancement; aRCE: Arterial relative contrast enhancement; pRCE: Portal phase relative contrast enhancement; dRCE: Delay phase relative contrast enhancement; MaRIA: Magnetic resonance index of activity; CDEIS: Crohn’s disease endoscopic index of severity; ESR: Erythrocyte sedimentation rate.