Regulatory polymorphism of CXCL10 rs1439490 in seronegative occult hepatitis C virus infection

Table 3 Clinical characteristics of patients enrolled in this study n (%)

	Seronegative OCI patients (n = 103)	Seropositive CHC patients (n = 155)	P value
Gender			0.664
Male	58 (56.3)	83 (53.5)
Female	45 (43.7)	72 (46.5)
Age (yr)	52.16 ± 7.64	42.70 ± 9.15	< 0.001
ALT (IU/L)	61.13 ± 23.54	93.17 ± 55.39	< 0.001
GGT	56.31 ± 16.63	52.86 ± 15.69	0.093
BMI	23.73 ± 2.38	24.12 ± 2.36	0.192
HOMA-IR	2.39 ± 0.15	2.42 ± 0.18	0.219
Transfusion/surgery/tattoo history	8 (7.8)	26 (16.8)	0.027
Family history of HCV infection	29 (28.2)	19 (12.3)	< 0.001
Intrahepatic HCV RNA (log10 IU/mL)	3.19 ± 1.05	5.48 ± 1.49	< 0.001
HCV genotype			0.89
Genotype 1	66 (64.1)	98 (63.2)
Non-genotype 1	37 (35.9)	57 (36.8)
Fibrosis (Fibroscan)			0.317
F0-1	65 (63.1)	104 (67.1)
F2-4	38 (36.9)	51 (32.9)
METAVIR activity score	1.14 ± 0.34	1.69 ± 0.68	< 0.001
METAVIR fibrosis score	1.82 ± 0.98	1.87 ± 1.07	0.673

P < 0.05; ALT: Alanine aminotransferase; GGT: Gamma-glutamyl transpeptidase; BMI: Body mass index; HOMA-IR: Homeostasis model assessment of insulin resistance; HCV non-genotype 1: Other HCV genotypes except for genotype 1, including HCV 2-6 genotypes.