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©The Author(s) 2018.
World J Gastroenterol. May 28, 2018; 24(20): 2181-2190
Published online May 28, 2018. doi: 10.3748/wjg.v24.i20.2181
Published online May 28, 2018. doi: 10.3748/wjg.v24.i20.2181
Table 2 Correlation of nuclear indoleamine-2,3-dioxygenase 1 expression with colorectal cancer clinicopathologic parameters
Characteristic | Total | Low IDO1 | High IDO1 | P-value |
Sex | 0.70 | |||
Male | 51 | 39 (76.5) | 12 (33.5) | |
Female | 44 | 36 (81.8) | 8 (19.2) | |
Age in yr | 0.92 | |||
> 60 | 30 | 24 (80.0) | 6 (20.0) | |
≤ 60 | 65 | 51 (78.5) | 14 (21.5) | |
Cancers | 0.52 | |||
Colon | 46 | 38 (82.6) | 18 (17.4) | |
Rectum | 49 | 37 (75.5) | 12 (24.5) | |
BMI | < 0.001 | |||
> 25 | 20 | 9 (45.0) | 11 (55.0) | |
≤ 25 | 75 | 66 (88.0) | 9 (12.0) | |
Tumor differentiation | 0.87 | |||
Moderate and poor | 78 | 60 (76.9) | 18 (23.1) | |
Well | 17 | 14 (82.3) | 3 (17.7) | |
Conlon cancer stage | 0.98 | |||
3 | 20 | 17 (85.0) | 3 (15.0) | |
2 | 26 | 21 (80.8) | 5 (19.2) | |
T stage | 0.71 | |||
4 | 29 | 23 (19.3) | 6 (20.7) | |
2/3 | 17 | 15 (88.2.) | 2 (11.8) | |
N stage | 0.98 | |||
1/2 | 20 | 16 (80.0) | 4 (20.0) | |
0 | 26 | 22 (84.6) | 4 (15.4) | |
Rectum cancer stage | 0.44 | |||
3 | 24 | 17 (70.8) | 7 (29.2) | |
2 | 25 | 21 (84.0) | 4 (16.0) | |
T stage | 0.94 | |||
4 | 22 | 16 (72.7) | 6 (27.3) | |
2/3 | 27 | 21 (77.8) | 6 (22.2) | |
N stage | 0.28 | |||
1/2 | 24 | 16 (66.7) | 8 (33.3) | |
0 | 25 | 21(84.0) | 4 (16.0) | |
CEA in ng/mL | 0.37 | |||
> 5 | 42 | 35 (83.3) | 7 (16.7) | |
≤ 5 | 53 | 39 (73.6) | 14 (26.4) | |
CA19-9 in U/mL | 0.78 | |||
> 37 | 81 | 41 (50.6) | 40 (49.4) | |
≤ 37 | 17 | 8 (47.1) | 9 (52.9) | |
CD3 TILs | 0.96 | |||
High | 36 | 28 (77.8) | 8 (22.2) | |
Low | 59 | 47 (79.7) | 12 (20.3) | |
CD8 TILs | 0.26 | |||
High | 22 | 15 (68.2) | 7 (31.8) | |
Low | 73 | 60 (82.2) | 13 (17.8) | |
COX2 | 0.84 | |||
High | 48 | 38 (79.2) | 10 (20.8) | |
Low | 47 | 37 (78.7) | 10 (21.3) | |
Treatment group | 0.16 | |||
Celecoxib | 44 | 38 (86.4) | 6 (13.6) | |
Non-celecoxib | 51 | 37 (72.5) | 14 (27.5) |
- Citation: Ma WJ, Wang X, Yan WT, Zhou ZG, Pan ZZ, Chen G, Zhang RX. Indoleamine-2,3-dioxygenase 1/cyclooxygenase 2 expression prediction for adverse prognosis in colorectal cancer. World J Gastroenterol 2018; 24(20): 2181-2190
- URL: https://www.wjgnet.com/1007-9327/full/v24/i20/2181.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i20.2181