Microbiota modification by probiotic supplementation reduces colitis associated colon cancer in mice

Figure 1 Probiotic supplementation reduces tumour incidence in a colorectal cancer model associated with colitis. Number (A) and size (B) of colon tumours in the control (n = 33) and probiotic (n = 29) groups. C: Representative images of tumours in the colons of the control and probiotic groups at day 60 after injection with azoxymethane. D: Change in body weight during treatment with azoxymethane and DSS in the control (n = 31) and probiotic (n = 31) groups. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001; Mann-whitney U test (A and D), Chi-square test (B). Data are from three independent experiments and are presented as mean and standard deviation.