Sodium chloride exacerbates dextran sulfate sodium-induced colitis by tuning proinflammatory and antiinflammatory lamina propria mononuclear cells through p38/MAPK pathway in mice

Figure 7 High NaCl levels enhance proinflammation gene expression in LPS-activated peritoneal macrophage. A-E: Peritoneal macrophages were stimulated with different NaCl concentrations (10-80 mmol/L) in the presence of LPS for 24 h. mRNA expression was measured by RT-PCR for the indicated genes. In all the panels, data indicate three separate experiments. ^aP < 0.05; ^bP < 0.01; ^cP < 0.001. LPS: Lipopolysaccharide.