Mucosa repair mechanisms of Tong-Xie-Yao-Fang mediated by CRH-R2 in murine, dextran sulfate sodium-induced colitis

doi:10.3748/wjg.v24.i16.1766

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 28, 2018; 24(16): 1766-1778
Published online Apr 28, 2018. doi: 10.3748/wjg.v24.i16.1766

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Figure 3 Inhibition of CRH-R2 signaling promotes intestinal permeability in DSS-induced colitis. The FITC-dextran levels in serum were determined. Data are presented as mean ± standard deviation, n = 6 per group. ^aP < 0.001 vs control group; ^gP < 0.05, ^bP < 0.001 vs DSS group; ^eP < 0.001 vs Ucn2 group; ^fP < 0.001 vs TXYF-L group; ^dP < 0.001 vs TXYF-M group; ^cP < 0.001 vs TXYF-H group. CRH-R2: Corticotropin-releasing hormone-receptor 2; DSS: Dextran sulfate sodium; TXYF: Tong-Xie-Yao-Fang.

Citation: Gong SS, Fan YH, Wang SY, Han QQ, Lv B, Xu Y, Chen X, He YE. Mucosa repair mechanisms of Tong-Xie-Yao-Fang mediated by CRH-R2 in murine, dextran sulfate sodium-induced colitis. World J Gastroenterol 2018; 24(16): 1766-1778
URL: https://www.wjgnet.com/1007-9327/full/v24/i16/1766.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i16.1766