Evaluation of safety for hepatectomy in a novel mouse model with nonalcoholic-steatohepatitis

Figure 2 Ki-67 staining and proliferation score. Proliferation was evaluated by Ki-67 staining. We compared preoperative nonalcoholic steatohepatitis (NASH) groups with NASH 30% PH and NASH 70% PH groups 6 h after PH. Ratios of Ki-67-positive/total hepatocytes were calculated. Significantly fewer Ki-67-positive cells were noted in the 70% PH group than in the NASH 30% PH group. Ratios (%) are expressed as the mean ± SD. n = 2 per groups, 10 fields per sample. ^aP < 0.05; ^bP < 0.01. Scale bar: 100 μm. PH: partial hepatectomy; NASH: nonalcoholic steatohepatitis.