Retrospective Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Apr 21, 2018; 24(15): 1641-1649
Published online Apr 21, 2018. doi: 10.3748/wjg.v24.i15.1641
Table 4 Comparisons in hepatocellular carcinoma patients among dichotomization of gamma glutamyl transpeptidase (≤ 100/> 100 IU/L), in the total cohort
GGTP (IU/L)
Parameter1≤ 100 (n = 81) (50.31%)> 100 (n = 80) (49.69%)P2 value
Total bilirubin (mg/dL)1.25 ± 0.751.19 ± 0.870.17
ALKP (IU/mL)104.55 ± 42.06160.92 ± 89.79< 0.0001
GGTP (IU/mL)55.44 ± 24.46250.29 ± 165.35< 0.0001
AST (IU/L)93.61 ± 79.10115.45 ± 137.270.06
Albumin (g/dL)3.70 ± 2.683.56 ± 0.570.13
Platelets (× 109/L)100.14 ± 61.45129.60 ± 100.060.02
Aggressiveness index (%)
Score > 433 (56.90)42 (75.00)0.043
Survival at time (%)
1 yr68 (87.18)54 (70.13)0.013
2 yr52 (66.67)37 (48.05)0.023
3 yr39 (50.00)25 (32.47)0.033
1All values: mean ± SD;
2Wilcoxon rank-sum (Mann-Whitney) test;
3Test Z for proportions. Aggressiveness index (sum of scores): MTD (in tertiles): MTD < 4.5; 4.5 ≤ MTD ≤ 9.6; MTD > 9.6; scores 1, 2, 3 respectively; AFP (cut-off): AFP < 100; 100 ≤ AFP ≤ 1000; AFP > 1000; scores 1, 2, 3 respectively; PVT (no/yes): PVT(no); PVT(yes); scores 1, 3 respectively; nodules (number): Nodules ≤ 3; nodules > 3; scores 1, 3 respectively. AFP: Alpha-fetoprotein; MTD: Maximum tumor diameter; PVT: Portal vein thrombosis; ALKP: Alkaline phosphatase; GGTP: Gamma glutamyl transpeptidae; AST: Aspartate aminotransaminase; Hb: Haemoglobin; Plt: Platelet count.