Evaluation of safety for hepatectomy in a novel mouse model with nonalcoholic-steatohepatitis

Table 1 Serum parameters of normal liver and nonalcoholic steatohepatitis groups after partial hepatectomy

	6 h after PH				12 h after PH
	AST	ALT	T-Bil	IL-6	AST	ALT	T-Bil	IL-6
Normal 70%PH	2343.3 ± 6160.4	1828.3 ± 990.4	1.43 ± 0.5	2036.0 ± 1470.9	2976.7 ± 1395.7	2053.3 ± 886.2	2.0 ± 0.9	731.5 ± 483.7
NASH 30%PH	1610.0 ± 3700.6	1507.1 ± 563.5	0.76 ± 0.2	1511.5 ± 284.8	1841.3 ± 619.1	1522.9 ± 537.9	0.9 ± 0.7	692.8 ± 211.1
NASH 70%PH	3064.3 ± 1289.8a	2422.9 ± 1194.8	2.57 ± 1.36b	3026.2 ± 2127.5	4067.5 ± 2059.2a	2403.8 ± 1111.8	3.85 ± 0.96b	987.9 ± 550.7

Data are presented as the mean ± SD (n = 5-7).

^aP < 0.05,

^bP < 0.01 vs other groups. NASH: Nonalcoholic steatohepatitis; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; PH: Partial hepatectomy; T-Bil: Total bilirubin; IL-6: Interleukin-6.