Punctual mutations in 23S rRNA gene of clarithromycin-resistant Helicobacter pylori in Colombian populations

Table 4 Punctual mutations in 23S rRNA gene of Helicobacter pylori from the population at high-risk of gastric cancer, according to susceptibility or resistance to clarithromycin

Resistant n = 4			Susceptible n = 6
Patient ID	Mutations	MIC	Patient ID	Mutations	MIC
323	A1593G/A1822G/G1827A/T1645C/T1831C/1T2183C	1	351	A1822G/G1827A/T1831C	< 0.25
336	A1593G/1C2196T	2	377	A1822G/G1827A/G2221A/T1645C/T1831C	< 0.25
339	1A2144G/G1827A	4	394	A1593G	< 0.25
440	A1822G/G1827A/G2221A/T1831C	4	457	A1822G/G1827A/G2221A/T1831C	< 0.25
			467	A1739G/G1695A	< 0.25
			513	A1822G/G1827A/T1831C	< 0.25
ATCC 700392	A1593G		ATCC 43504	A1667G/T1668C

¹Unique mutations of Helicobacter pylori resistant to clarithromycin. MIC: Minimum inhibitory concentration (μg/mL).