Retrospective Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Apr 7, 2018; 24(13): 1451-1463
Published online Apr 7, 2018. doi: 10.3748/wjg.v24.i13.1451
Table 2 Correlation between fibrinogen concentration and clinicopathological characteristics in gallbladder carcinoma patients n (%)
CharacteristicsFibrinogen concentration
P value
≤ 3.47 g/L (n = 75)> 3.47 g/L (n = 79)
Age (yr)
≤ 6031 (20.1)25 (16.2)0.243
> 6044 (28.6)54 (35.1)
Sex
Male33 (21.4)30 (19.5)0.513
Female42 (27.3)49 (31.8)
Cholecystolithiasis
Absent38 (24.7)41 (26.6)0.878
Present37 (24.0)38 (24.7)
Diabetes
Absent57 (37.0)59 (38.3)0.850
Present18 (11.7)20 (13.0)
Jaundice
Absent68 (44.2)61 (39.6)0.029
Present7 (4.5)18 (11.7)
Blood groups
A19 (12.3)24 (15.6)0.145
B33 (21.4)23 (14.9)
AB2 (1.3)7 (4.5)
O21 (13.6)25 (16.2)
Pathological types
Adenosquamous carcinoma0 (0)3 (1.9)0.142
Adenocarcinoma75 (48.7)75 (48.7)
Papillocarcinoma0 (0)1 (0.6)
Degree of differentiation
Poor23 (14.9)37 (24.0)0.048
Moderate-well52 (33.8)42 (27.3)
Resection margin status
Negative56 (36.4)40 (26.4)0.003
Positive19 (12.3)39 (25.3)
Maximum tumor diameter (cm)
≤ 2.4534 (22.1)34 (22.1)0.871
> 2.4541 (26.6)45 (29.2)
T stage
Tis-T1a8 (5.2)2 (1.3)< 0.001
T1b-T2b22 (14.3)7 (4.5)
T343 (27.9)60 (39.0)
T42 (1.3)10 (6.5)
N stage
N050 (32.5)48 (31.2)0.748
N121 (13.6)26 (16.9)
N24 (2.6)5 (3.2)
Distant metastasis
Absent69 (44.8)73 (47.4)0.925
Present6 (3.9)6 (3.9)
TNM stage
0-I stage12 (7.8)4 (2.6)0.011
IIA-IIB stage12 (7.8)4 (2.6)
IIIA-IIIB stage39 (25.3)53 (34.4)
IVA-IVB stage12 (7.8)18 (11.7)
CA199 (U/mL)
≤ 25.4537 (24.0)20 (13.0)0.003
> 25.4538 (24.7)59 (38.3)