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©The Author(s) 2018.
World J Gastroenterol. Apr 7, 2018; 24(13): 1410-1418
Published online Apr 7, 2018. doi: 10.3748/wjg.v24.i13.1410
Published online Apr 7, 2018. doi: 10.3748/wjg.v24.i13.1410
Table 1 Patients’ demographics and laboratory with n = 52 demonstrating autoimmune hepatitis-induced acute liver failure (9.2%)
| Study population (n = 52) with AIH-induced ALF | |
| Mean age (yr) | 43.6 ± 14.9 (19-76) |
| Male | 8 (15.4%) |
| Female | 44 (84.6%) |
| Hepatic encephalopathy | Grade I: 46/52 (88.4%) |
| Grade II: 2/52 (3.8%) | |
| Grade III: 2/52 (3.8%) | |
| Grade IV: 2/52 (3.8%) | |
| Immunosuppressive therapy | Steroid induction: 52/52 (100%) |
| Steroid maintenance: 30/52 (57.7%) | |
| Steroid withdrawal: 20/52 (42.3%) | |
| Azathioprine: 27/52 (51.9%) | |
| Cyclosporine A: 7/52 (13.5%) | |
| ALT (U/L) | 1391.0 (843.5-2154.5) |
| Total bilirubin (mg/dL) | 14.3 (11.7-18.7) |
| Creatinine (mg/dL) | 0.76 (0.55-0.95) |
| INR | 1.78 (1.64-2.00) |
| LabMELD-score | 24 (22-26) |
| Immunoglobulin G (g/L) | 17.2(13.1-22.8) |
| γ-globulin-fraction (%) | 24.5 (19.5-29.3) |
- Citation: Buechter M, Manka P, Heinemann FM, Lindemann M, Baba HA, Schlattjan M, Canbay A, Gerken G, Kahraman A. Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients. World J Gastroenterol 2018; 24(13): 1410-1418
- URL: https://www.wjgnet.com/1007-9327/full/v24/i13/1410.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i13.1410