Retrospective Cohort Study
Copyright ©The Author(s) 2018.
World J Gastroenterol. Mar 28, 2018; 24(12): 1321-1331
Published online Mar 28, 2018. doi: 10.3748/wjg.v24.i12.1321
Table 8 Multivariate model of biomarkers and tumor size at time of transplant (S-LAD)
VariableHazard ratio for recurrence
Hazard ratio for death
HR (95%CI)P valueHR (95%CI)P value
Diameter of the largest tumor at time of transplant (per cm)1.30 (1.05-1.61)0.02a1.29 (1.08-1.55)0.006b
AFP: > 400 ng/mL1.63 (0.70-3.83)0.262.40 (1.19-4.83)0.02a
AFP-L3 > 15%0.995 (0.46-2.18)0.991.01 (0.54-1.88)0.98
DCP > 1.2 ng/mL2.69 (1.28-5.64)0.009b2.33 (1.31-4.13)0.004b
c-statistic (95%CI)0.71 (0.62-0.81)0.69 (0.61-0.77)

  • Citation: Wongjarupong N, Negron-Ocasio GM, Chaiteerakij R, Addissie BD, Mohamed EA, Mara KC, Harmsen WS, Theobald JP, Peters BE, Balsanek JG, Ward MM, Giama NH, Venkatesh SK, Harnois DM, Charlton MR, Yamada H, Algeciras-Schimnich A, Snyder MR, Therneau TM, Roberts LR. Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models. World J Gastroenterol 2018; 24(12): 1321-1331
  • URL: https://www.wjgnet.com/1007-9327/full/v24/i12/1321.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v24.i12.1321