Epidemiological features of chronic hepatitis C infection caused by remunerated blood donors: A nearly 27-year period survey

Table 1 Demographic and clinical characteristics of remunerated blood donors

	Blood donors, n = 363	Single plasma donors, n = 780	Blood and plasma donors, n = 551	P value
Age in yr	56.8 ± 13.2	57.2 ± 11.3	57.1 ± 9.4	0.8821
≥ 40, < 50	56 (15.4)	83 (10.6)	68 (12.3)	0.07
≥ 50, < 60	203 (55.9)	501 (64.2)	336 (61.0)
≥ 60	104 (28.7)	196 (25.1)	147 (26.7)
Sex
Male	123 (33.92)	315 (36.5)	211 (38.3)	0.1092
Female	240 (66.1)	465 (63.5)	340 (61.5)
BMI	25.52 ± 4.32	25.36 ± 4.11	25.45 ± 3.22	0.3531
< 25	178 (49)	395 (50.6)	294 (53.4)	0.1672
≥ 25, < 28	130 (35.8)	284 (36.4)	169 (30.7)
≥ 28	55 (15.2)	101 (12.9)	88 (16)
PLT as × 109/L	207.3 ± 64.8	161.8 ± 55.4	176.3 ± 63.1	< 0.0011
ALB in g/L	42.3 ± 3.5	41.4 ± 4.7	43.3 ± 4.5	0.5131
ALT in U/L	27.4 ± 6.5	63.2 ± 18.7	52.6 ± 15.4	< 0.0011
AST in U/L	23.5 ± 7.4	55.4 ± 12.9	44.5 ± 22.6	< 0.0011
Anti-HCV
Positive	12 (3.3)	534 (68.5)	324 (58.8)	< 0.0012
Negative	351 (96.7)	246 (31.5)	227 (41.29)
HBsAg
Positive	2 (0.6)	3 (0.4)	1 (0.2)	0.6433
Negative	361 (99.4)	777 (99.6)	550 (99.8)
LSM in kPa	5.56 ± 2.64	7.37 ± 3.62	6.54 ± 3.54	< 0.0011
≥ 9	2 (0.6)	224 (28.7)	122 (22.1)	< 0.0012
< 9, ≥ 6	20 (5.5)	313 (40.1)	287 (52.1)
< 6	341 (93.9)	243 (31.2)	142 (25.8)
Blood donated frequency times
≥ 10	212 (58.4)	245 (31.4)	187 (33.9)	< 0.0012
< 10, ≥ 5	120 (33.1)	352 (45.1)	202 (36.7)
< 5	31 (8.5)	183 (23.5)	162 (29.4)
Interval time from last donated blood to survey in yr	27.56 ± 2.11	27.65 ± 3.02	27.84 ± 2.54	0.4531
Refused donated by elevated ALT
Yes	37 (10.2)	317 (40.6)	195 (35.4)	< 0.0012
No	326 (89.8)	463 (59.4)	356 (64.6)

Data are presented as n (%). The normal range of ALT and AST are 5-40 U/L, PLT is 100-300 × 10⁹/L, ALB is 35-55 g/L.

¹One-way analysis;

²Pearson Chi-Squared;

³Fisher’s exact test. ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BMI: Body mass index; LSM: Liver stiffness measurement; PLT: Platelet.