Copyright
©The Author(s) 2018.
World J Gastroenterol. Mar 21, 2018; 24(11): 1239-1249
Published online Mar 21, 2018. doi: 10.3748/wjg.v24.i11.1239
Published online Mar 21, 2018. doi: 10.3748/wjg.v24.i11.1239
Table 4 Diagnostic performance of autotaxin and conventional fibrosis indicators for predicting severe fibrosis (≥ F3) in patients with non-alcoholic fatty liver disease
AUC | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Accuracy (%) | |
All patients | ||||||
ATX | 0.75 | 51 | 91 | 63 | 86 | 82 |
HA | 0.82 | 93 | 63 | 44 | 96 | 70 |
4C7S | 0.87 | 75 | 88 | 64 | 92 | 85 |
APRI | 0.82 | 60 | 89 | 62 | 88 | 82 |
FIB-4 | 0.85 | 79 | 74 | 48 | 92 | 75 |
Male | ||||||
ATX | 0.74 | 62 | 82 | 40 | 92 | 79 |
HA | 0.76 | 85 | 72 | 41 | 95 | 75 |
4C7S | 0.81 | 69 | 89 | 56 | 94 | 86 |
APRI | 0.74 | 77 | 64 | 29 | 93 | 66 |
FIB-4 | 0.81 | 92 | 75 | 41 | 98 | 78 |
Female | ||||||
ATX | 0.78 | 73 | 86 | 67 | 89 | 82 |
HA | 0.86 | 78 | 86 | 68 | 91 | 83 |
4C7S | 0.89 | 78 | 90 | 75 | 92 | 87 |
APRI | 0.86 | 63 | 95 | 83 | 87 | 86 |
FIB-4 | 0.85 | 80 | 75 | 56 | 90 | 76 |
- Citation: Fujimori N, Umemura T, Kimura T, Tanaka N, Sugiura A, Yamazaki T, Joshita S, Komatsu M, Usami Y, Sano K, Igarashi K, Matsumoto A, Tanaka E. Serum autotaxin levels are correlated with hepatic fibrosis and ballooning in patients with non-alcoholic fatty liver disease. World J Gastroenterol 2018; 24(11): 1239-1249
- URL: https://www.wjgnet.com/1007-9327/full/v24/i11/1239.htm
- DOI: https://dx.doi.org/10.3748/wjg.v24.i11.1239