Differing profiles of people diagnosed with acute and chronic hepatitis B virus infection in British Columbia, Canada

Table 3 Multivariable multinomial regression model (with interaction terms) for factors associated with acute or chronic hepatitis B virus in the British Columbia Hepatitis Testers Cohort, 1990-2015

	Adjusted OR (95% CI)
	Acute HBV	Chronic HBV
Sex
Male	2.30 (2.08-2.54)	1.43 (1.4-1.46)
Female	1.00	1.00
HCV
Positive	5.22 (4.65-5.86)	2.88 (2.77-3.00)
Negative	1.00	1.00
HIV
Positive	5.25 (4.26-6.47)	5.75 (5.31-6.22)
Negative	1.00	1.00
Active tuberculosis
Yes	0.58 (0.31-1.08)	0.97 (0.86-1.10)
No	1.00	1.00
Problematic alcohol use
Yes	0.90 (0.75-1.07)	1.01 (0.95-1.07)
No	1.00	1.00
Major mental illness
Yes	0.72 (0.61-0.84)	0.75 (0.71-0.78)
No	1.00	1.00
Social deprivation quintile
Q2-Q4	1.21 (1.05-1.40)	0.97 (0.94-1.00)
Q5 (most deprived)	1.58 (1.36-1.84)	0.99 (0.96-1.03)
Q1 (most privileged)	1.00	1.00
IDU*Age at HBV diagnosis (yr)
IDU* < 25	7.55 (5.13-11.10)	1.43 (1.18-1.73)
IDU*25-34	5.32 (4.08-6.94)	1.72 (1.55-1.91)
IDU*35-44	2.98 (2.26-3.93)	1.87 (1.71-2.05)
IDU*45-54	1.77 (1.19-2.62)	2.06 (1.87-2.28)
IDU*55+	1.56 (0.78-3.10)	2.34 (2.05-2.65)
No IDU* < 25	2.23 (1.84-2.71)	0.90 (0.86-0.93)
No IDU*25-34	2.53 (2.13-3.01)	1.11 (1.07-1.15)
No IDU*35-44	1.84 (1.54-2.19)	1.21 (1.17-1.25)
No IDU*45-54	1.57 (1.30-1.90)	1.24 (1.20-1.28)
No IDU*55+	1.00	1.00
Ethnicity*Material Deprivation quintile
East Asian*Material deprivation Q2-Q4	1.71 (1.37-2.12)	13.39 (12.82-13.98)
East Asian*Material deprivation Q5	2.61 (2.06-3.32)	15.98 (15.23-16.77)
East Asian*Material deprivation Q1	2.05 (1.49-2.81)	11.69 (11.07-12.33)
Other*Material deprivation Q2-Q4	0.97 (0.60-1.57)	3.32 (3.07-3.60)
Other*Material deprivation Q5	1.15 (0.59-2.26)	4.23 (3.78-4.74)
Other*Material deprivation Q1	0.89 (0.44-1.81)	2.62 (2.32-2.95)
South Asian*Material deprivation Q2-Q4	1.81 (1.35-2.42)	1.42 (1.30-1.54)
South Asian*Material deprivation Q5	2.44 (1.81-3.30)	1.41 (1.28-1.56)
South Asian*Material deprivation Q1	1.02 (0.48-2.19)	1.55 (1.32-1.82)
White*Material deprivation Q2-Q4	1.08 (0.94-1.25)	1.03 (0.98-1.08)
White*Material deprivation Q5	1.33 (1.13-1.56)	1.36 (1.29-1.43)
White*Material deprivation Q1	1.00	1.00
Year of HBV diagnosis
1990-1999	1.00	1.00
2000-2004	0.10 (0.09-0.12)	0.27 (0.26-0.28)
2005-2009	0.03 (0.03-0.04)	0.14 (0.13-0.14)
2010-2015	0.00 (0.00-0.01)	0.05 (0.05-0.06)

IDU: Injection drug use; HIV: Human immunodeficiency virus; HCV: Hepatitis C virus; HBV: Hepatitis B virus; Q: Quintile.