Three-microRNA signature identified by bioinformatics analysis predicts prognosis of gastric cancer patients

Table 3 Association between the three differentially expressed miRNAs and clinical features

Variables	miR-145-3p expression		P value	miR-125b-5p expression		P value	miR-99a-5p expression		P value
	Low	High		Low	High		Low	High
Age at diagnosis (yr)
< 60	51	62	0.225	42	71	0.001a	49	64	0.096
≥ 60	129	119		138	110		131	117
T stage
T1 + T2	40	48	0.342	51	37	0.081	46	42	0.603
T3 + T4	140	133		129	144		134	139
N stage
N0	58	53	0.567	57	54	0.731	57	54	0.731
N1-3	119	124		120	123		120	123
M stage
M0	163	162	0.670	165	160	0.191	164	161	0.386
M1	10	12		8	14		9	13
Histologic grade
G1 + G2	77	57	0.026a	87	47	< 0.001a	80	54	0.004a
G3 + G4	103	124		93	134		100	127
Pathologic stage
I + II	81	80	0.876	86	75	0.221	80	81	0.954
III + IV	95	97		90	102		96	96

^aP < 0.05, statistically significant.