Proteinase-activated receptor 2 promotes tumor cell proliferation and metastasis by inducing epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma

doi:10.3748/wjg.v24.i10.1120

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 24, Issue 10

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (7678)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-7) series, Tables (1-3) series.

Item

Count

PDF

505

WORD

222

HTML

4461

Figures (1-7)

287

Tables (1-3)

227

Sum=5702

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

856

Download

1120

Sum=1976

Mar 14, 2018 (publication date) through Nov 8, 2024

Times Cited of This Article

Times Cited (16)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Basic Study

World J Gastroenterol. Mar 14, 2018; 24(10): 1120-1133
Published online Mar 14, 2018. doi: 10.3748/wjg.v24.i10.1120

Full Size Figure Download Figure

Figure 7 Proteinase-activated receptor 2 mediates the activation of ERK and further induces epithelial-mesenchymal transition. A: The protein levels of ERK and p-ERK in HepG2 and SMMC-7721 cells; B: The morphological changes in HepG2 and SMMC-7721 cells after proteinase-activated receptor 2 knockdown; C and D: The protein levels of EGR-1, Snail, E-cadherin, and N-cadherin in HepG2 and SMMC-7721 cells. GAPDH was selected as an endogenous control.

Citation: Sun L, Li PB, Yao YF, Xiu AY, Peng Z, Bai YH, Gao YJ. Proteinase-activated receptor 2 promotes tumor cell proliferation and metastasis by inducing epithelial-mesenchymal transition and predicts poor prognosis in hepatocellular carcinoma. World J Gastroenterol 2018; 24(10): 1120-1133
URL: https://www.wjgnet.com/1007-9327/full/v24/i10/1120.htm
DOI: https://dx.doi.org/10.3748/wjg.v24.i10.1120