Emodin and baicalein inhibit sodium taurocholate-induced vacuole formation in pancreatic acinar cells

Figure 3 CEB inhibits sodium taurocholate-induced Ca²⁺ overload in isolated pancreatic acinar cells. Cell fluorescence intensity represents the cell calcium concentration. A: Dynamic change in the calcium concentration induced by sodium taurocholate was inhibited by CEB: (a) Unaltered fluorescence intensity over time in the control group. (b) Cell fluorescence intensity was strengthened immediately within 2 s of the sodium taurocholate irritation and lasted at a high calcium concentration for 30 s, followed by a decrease in the SAP group. (c) Cell fluorescence intensity was increased within the first 2 s after the sodium taurocholate suscitation, was sustained at a high calcium concentration for 5 s, and then began to decrease in the CEB group. B: Cell images at representative time points. (a) Control group. (b) SAP group. (c) CEB group.