Correlation between smoking habit and surgical outcomes on viral-associated hepatocellular carcinomas

Table 6 Comparison of clinicopathological factors per current smoking status in the hepatitis C virus-related hepatocellular carcinoma and hepatitis B virus-related hepatocellular carcinoma patient group

	HCV (n = 273)			HBV (n = 68)
	Current (n = 88)	Never + Ex (n = 185)	P value	Current (n = 32)	Never + Ex (n = 36)	P value
Age (mean ± SD)	65.34 ± 7.82	68.02 ± 8.77	0.0153	53.66 ± 13.74	60.25 ± 10.46	0.0284
Gender (male/female)	81/7	122/63	< 0.0001	31/1	28/8	0.0204
Alcohol abuse (+/-)	35/53	28/157	< 0.0001	13/19	9/27	0.1692
Diabetes mellitus (+/-)	20/68	42/143	0.9964	5/27	7/29	0.6801
BMI (mean ± SD)	21.71 ± 2.74	22.87 ± 3.47	0.0031	23.01 ± 3.89	22.85 ± 3.77	0.8656
ICG R15 (%)	16.14 ± 7.24	19.81 ± 9.56	0.0005	12.54 ± 5.25	14.00 ± 7.11	0.3451
AFP (ng/mL), median (range)	20.5 (2, 29800)	29 (0, 19500)	0.4338	64.9 (1, 271600)	14.8 (2.4, 209900)	0.7995
Tumor size (mean ± SD mm)	39.25 ± 25.87	36.48 ± 25.52	0.4050	47.69 ± 29.26	51.53 ± 36.56	0.6369
Solitary/Multiple	60/28	122/63	0.7142	17/15	24/12	0.2546
Vp (+/-)	28/60	46/139	0.2271	13/19	16/20	0.7506
T factor (T12/T34)	48/40	108/77	0.5498	15/17	17/19	0.9772
Recurrence (+/-)	59/29	138/47	0.1934	20/12	20/16	0.5614

HCV: Hepatitis C virus; HBV: Hepatitis B virus; BMI: Body mass index; AFP: Alpha-fetoprotein.