miR-1181 inhibits invasion and proliferation via STAT3 in pancreatic cancer

Figure 4 miR-1181 inhibits invasion and proliferation via STAT3 in pancreatic cancer cells. A: Indicated cells were subjected to Western blot assay to detect STAT3 and p-STAT3 expression; B: We designed 3 siRNA targeted STAT3 and verified by PCR, ^aP < 0.05; C: Indicated PANC-1 cells were subjected to CCK-8 assays, ^cP < 0.05; D: Indicated MIA-PaCa-2 cells were subjected to CCK-8 assays, ^aP < 0.05; E: Indicated PANC-1 cells were subjected to transwell assays and relative migration and invasion capability was quantitative analyzed (F and G), ^eP < 0.001, ^fP < 0.001; H: Indicated MIA-PaCa-2 cells were subjected to transwell assays and relative migration and invasion capability was quantitative analyzed (I and J), ^eP < 0.001, ^fP < 0.001.