miR-1181 inhibits invasion and proliferation via STAT3 in pancreatic cancer

Figure 2 miR-1181 inhibited pancreatic cancer cell migration and invasion. A: Indicated PANC-1 cells were subjected to transwell assays and relative migration and invasion capability was quantitative analyzed (B and C), ^aP < 0.05; D: Indicated MIA-PaCa-2 cells were subjected to transwell assays and relative migration and invasion capability was quantitative analyzed (E and F), ^aP < 0.05; G and I: Indicated PANC-1 and MIA-PaCa-2 (H and J) cells were subjected to wound-healing assays and quantitative analyzed, ^aP < 0.05, ^bP < 0.01, ^eP < 0.001; K: Immunofluorescence staining shows decreased F-actin and β-tubulin expression in PANC-1 cells over-expressing miR-1181 compared with the blank control and negative control (NC) cells.