Proton pump inhibitor induced collagen expression in colonocytes is associated with collagenous colitis

Figure 1 Effect of proton pump inhibitor and/or alkaline pH on CT26 cell growth. Cell growth of CT26 cells was examined in different concentration of glucose (Glc) concentration (0, 100, 450 mg/dL). A: Pantoprazole (10 μg/mL) treatment (PPI); B: DMEM-pH8.0 treatment (pH 8.0); and C: Treatment with PPI and alkaline media (pH 8.0). Error bar, SD calculated from 3 independent experiments by Student's t-test. PPI: Proton pump inhibitor. ^bP < 0.001.