Outcomes of gastrointestinal defect closure with an over-the-scope clip system in a multicenter experience: An analysis of a successful suction method

Table 8 Current clinical outcomes of over-the-scope clips for each indication

Ref.	Year	Country	Patients (n)	Overall clinical success rate, (success/ total)					Mean defect size (mm)	Described data of suction method	Complications, n (%)
				Refractory bleeding	Leaks and/or perforations	Fistula	Others	Total
Albert et al[20]	2011	Germany	19	57.1 (4/7)	87.5 (7/8)	25 (1/4)	-	63.2	Unknown	Unknown	0
Surace et al[21]	2011	France, Monaco	19	-	-	74 (14/19)	-	73.7	Unknown	Unknown	1 (5)
Kirschniak et al[22]	2011	Germany	50	92.6 (25/27)	100 (11/11)	37.5 (3/8)	100 (4/4)	86	6	Unknown	0
Baron et al[19]	2012	United States	45	100 (7/7)	62.5 (5/8)	67.9 (19/28)	50 (1/2)	71	Unknown	TG: 8 cases AC: 17 cases	2 (4.4)
Manta et al[23]	2013	Italy	30	90 (27/30)	-	-	-	90	Unknown	Unknown	0
Haito-Chavez et al[15]	2014	International2	188	-	Leaks 73.3 (22/30), 21 Perforations 90 (36/40), 81	42.9 (39/91), 171	-	60.2	Leaks: 8 Perforations: 7 Fistula: 5	Use of TG and/or AC, 50% (70/140 cases)3	0
Law et al[24]	2014	United States	47	-	-	53 (25/47)	-	53	Unknown	Unknown	0
Sulz et al[25]	2014	Switzerland	21	100 (1/1)	66.7 (4/6)	63.6 (7/11)	100 (3/3)	71.4	8	SS:4 100% (10/10) TG:100% (1/1) AC: 87.5% (7/8) TG + AC: 0% (0/1)	0
Mercky et al[26]	2015	France, Monaco	30	-	-	53 (16/30)	-	53	7.2	SS: 17 procedures TG: 9 procedures AC: 5 procedures	4 (13.3)
Our study	2016	Japan	58	83.3 (15/18)	85.7 (24/28)	83.3 (10/12)	-	84.5	19.6	CSR SS4: 78.6% (11/14) TG: 88.1% (37/42) AC: 50% (1/2)	1 (1.8)
Total			507	87.8 (79/90)	83.2 (109/131)	53.0 (133/251)	88.9 (8/9)	68.4 (329/481)			8/481 (1.66)

¹Excluded number of patients lost to follow-up;

²United States, Netherlands, Germany, Italy, and Chile;

³Use of accessory devices was not a predictor of clinical success;

⁴Clinical success rate. SS: Simple suction; TG: Twin Grasper; AC: Anchor.