Proteomic profiling of fetal esophageal epithelium, esophageal cancer, and tumor-adjacent esophageal epithelium and immunohistochemical characterization of a representative differential protein, PRX6

doi:10.3748/wjg.v23.i8.1434

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2017; 23(8): 1434-1442
Published online Feb 28, 2017. doi: 10.3748/wjg.v23.i8.1434

Table 2 Expression of PRX6 protein in different types of esophageal lesions n (%)

Tissue	PRX6
Tissue	No. of cases	Negative	Positive
Tumor-adjacent
NOR	37	3 (8)	34 (92)
BCH	37	3 (8)	34 (92)
DYS	29	18 (62)	11 (38)
CIS	28	22 (79)	6 (21)
Esophageal cancer
W-SCC	7	0	7 (100)
M-SCC	16	3 (19)	13 (81)
P-SCC	6	5 (83)	1 (17)

P < 0.05, NOR vs DYS, CIS, M-SCC or P-SCC; BCH vs CIS, DYS, M-SCC or P-SCC; DYS vs W-SCC or M-SCC; CIS vs W-SCC or M-SCC; P-SCC vs W-SCC or M-SCC. NOR: Normal; BCH: Basal cell hyperplasia; DYS: Dysplasia; CIS: Carcinoma in situ; W-SCC: Well differentiated squamous cell carcinoma; M-SCC: Moderately differentiated; P-SCC: Poorly differentiated.

Citation: Guo JH, Xing GL, Fang XH, Wu HF, Zhang B, Yu JZ, Fan ZM, Wang LD. Proteomic profiling of fetal esophageal epithelium, esophageal cancer, and tumor-adjacent esophageal epithelium and immunohistochemical characterization of a representative differential protein, PRX6. World J Gastroenterol 2017; 23(8): 1434-1442
URL: https://www.wjgnet.com/1007-9327/full/v23/i8/1434.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i8.1434