Copyright
©The Author(s) 2017.
World J Gastroenterol. Feb 28, 2017; 23(8): 1387-1396
Published online Feb 28, 2017. doi: 10.3748/wjg.v23.i8.1387
Published online Feb 28, 2017. doi: 10.3748/wjg.v23.i8.1387
Study cohort | Older (age ≥ 80 yr) | Younger (age < 80 yr) | P value | |
(n = 350) | (n = 175) | (n = 175) | ||
Tumor location2 | ||||
Right colon | 140 (40) | 80 (45.7) | 60 (34.3) | 0.029 |
Left colon/rectum | 210 (60) | 95 (54.3) | 115 (65.7) | |
Histology | 0.201 | |||
NOS | 260 (76.5) | 124 (74.2) | 136 (78.6) | |
Mucinous | 64 (18.8) | 38 (22.8) | 26 (15) | |
Signet ring cell | 11 (3.2) | 3 (1.8) | 8 (4.6) | |
Other | 5 (1.5) | 2 (1.2) | 3 (1.78) | |
Grade3 | 0.025 | |||
1 | 48 (14.8) | 17 (10.4) | 31 (19.3) | |
2-3 | 276 (85.2) | 146 (89.3) | 130 (80.7) | |
T | 0.27 | |||
T1 | 17 (5.2) | 5 (3.1) | 12 (7.4) | |
T2 | 57 (17.6) | 28 (17.4) | 29 (17.8) | |
T3 | 237 (73.2) | 123 (76.4) | 114 (69.9) | |
T4 | 13 (4) | 5 (3.1) | 8 (4.9) | |
N | 0.357 | |||
N0 | 179 (67) | 94 (71.2) | 85 (63) | |
N1 | 56 (21) | 24 (18.2) | 32 (23.7) | |
N2 | 32 (12) | 14 (10.6) | 18 (13.3) | |
M1 | 72 (20.7) | 34 (19.8) | 38 (21.7) | 0.655 |
TNM stage | 0.259 | |||
I | 65 (19) | 30 (17.7) | 35 (20.2) | |
II | 116 (33.8) | 66 (38.8) | 50 (28.9) | |
III | 90 (26.2) | 40 (23.5) | 50 (28.9 ) | |
IV | 72 (21) | 34 (20) | 38 (22) | |
LVI | 18 (6) | 11 (7.5) | 7 (4.6) | 0.296 |
VVI | 36 (11.9) | 15 (10.1) | 21 (13.6) | 0.348 |
Obstruction4 | 36 (10.3) | 22 (12.6) | 14 (8) | 0.159 |
Perforation4 | 12 (3.4) | 10 (5.7) | 2 (1.1) | 0.019 |
Synchronous CRC | 11 (3.1) | 4 (2.3) | 7 (4) | 0.358 |
Metachronous CRC | 2 (0.6) | 1 (0.6) | 1 (0.6) | 0.997 |
RAS mutated | 8 (22.2) | 2 (15.4) | 6 (26.1) | 0.458 |
BRAF mutated | 1 (3.7) | 0 (0) | 1 (7.7) | 0.29 |
MSI-H | 6 (25) | 3 (100) | 3 (14.3) | 0.001 |
- Citation: Goldvaser H, Katz Shroitman N, Ben-Aharon I, Purim O, Kundel Y, Shepshelovich D, Shochat T, Sulkes A, Brenner B. Octogenarian patients with colorectal cancer: Characterizing an emerging clinical entity. World J Gastroenterol 2017; 23(8): 1387-1396
- URL: https://www.wjgnet.com/1007-9327/full/v23/i8/1387.htm
- DOI: https://dx.doi.org/10.3748/wjg.v23.i8.1387