Autoantibody profiles in autoimmune hepatitis and chronic hepatitis C identifies similarities in patients with severe disease

Table 7 Comparison between liver/kidney microsomal-1 positive patients in chronic hepatitis C and autoimmune hepatitis groups (mean ± SD)

Parameters	Groups		P value
	LKM-1+ in AIH	LKM-1+ in CHC
	M/F (0/9)	M/F (5/6)
Mean age (yr)	31 ± 10	35 ± 19	0.51 NS
IgG (mg/dL)	2205 ± 566.1	2522 ± 295.6	0.34 NS
IgM (mg/dL)	262 ± 41.21	185 ± 26.26	0.0011
AP (U/mL)	404 ± 146.7	472 ± 3	0.57 NS
AST (U/mL)	64 ± 12.71	57 ± 37.92	0.22 NS
ALT (U/mL)	41 ± 9.64	40 ± 5.41	0.45 NS
S. Albumin (g/dL)	3.4 ± 0.8	3.9 ± 0.9	0.5 NS
TSB (mg/dL)	3.4 ± 4.97	1.9 ± 3.90	0.06 NS

¹Indicates significant difference on the 0.01 level, NS indicates non-significance. Statistically significant differences were determined using analysis of variance followed by Duncan’s test. CHC: Chronic hepatitis C; AIH: Autoimmune hepatitis; AP: Alkaline phosphatase; AST: Aspartate transaminase; TSB: Total serum bilirubin; ALT: Alanine transaminase; LKM-1: Liver/kidney microsomal-1.