Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation

doi:10.3748/wjg.v23.i7.1171

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Feb 21, 2017 (publication date) through Jul 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 21, 2017; 23(7): 1171-1179
Published online Feb 21, 2017. doi: 10.3748/wjg.v23.i7.1171

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Figure 3 Thymoquinone inhibits β-catenin nuclear translocation in the LoVo cancer cell line. Nuclear isolation showed a decrease in β-catenin translocation into the nucleus. The cofactors LEF-1 and TCF-4 decreased in the nucleus following TQ treatment in a dose-dependent manner. TQ: Thymoquinone.

Citation: Hsu HH, Chen MC, Day CH, Lin YM, Li SY, Tu CC, Padma VV, Shih HN, Kuo WW, Huang CY. Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation. World J Gastroenterol 2017; 23(7): 1171-1179
URL: https://www.wjgnet.com/1007-9327/full/v23/i7/1171.htm
DOI: https://dx.doi.org/10.3748/wjg.v23.i7.1171